Can Bordetella cause pneumonia?

Bordetella bronchiseptica can be a cause of virulent pneumonia in humans with impaired immune systems. Few cases have been reported in the medical literature where Bordetella bronchiseptica has been the only pathogen isolated during a course of interstitial pneumonia.

What causes Bordetella bronchiseptica?

Disease Overview Bordetella (also referred to as tracheobronchitis, canine cough [in dogs], and feline bordetellosis [in cats]) is a highly contagious respiratory disease in cats and dogs caused by the bacteria Bordetella bronchiseptica. It causes inflammation of the trachea and bronchi.

Is Bordetella bronchiseptica a pathogen?

PATHOGENICITY/TOXICITY: B. bronchiseptica is primarily a respiratory tract pathogen found in a variety of animals 5.

Can Bordetella cause pneumonia in dogs?

Bordetella bronchiseptica and canine influenza virus (CIV) are common causes of infectious tracheobronchitis and, occasionally, pneumonia. Combined, these and other pathogens cause the canine infectious respiratory disease complex (CIRDC), often referred to as kennel cough or infectious tracheobronchitis.

Is Bordetella bronchiseptica kennel cough?

This is because Bordetella bronchiseptica is the most common bacterial agent responsible for kennel cough in dogs. Bordetella bronchiseptica causes inflammation of your dog’s upper respiratory system. This inflammation leads to coughing and illness and can expose your dog to secondary infections.

What causes pneumonia?

Viruses, bacteria, and fungi can all cause pneumonia. In the United States, common causes of viral pneumonia are influenza, respiratory syncytial virus (RSV), and SARS-CoV-2 (the virus that causes COVID-19). A common cause of bacterial pneumonia is Streptococcus pneumoniae (pneumococcus).

What is the structure of Bordetella bronchiseptica?

Structure. The bordetellae are small, Gram-negative, aerobic coccobacilli. Bordetella pertussis produces a number of virulence factors, including pertussis toxin, adenylate cyclase toxin, filamentous hemagglutinin, and hemolysin. Agglutinogens and other outer membrane proteins are important antigens.

Is Bordetella bronchiseptica motile?

Of the three Bordetella species, Bordetella pertussis and Bordetella parapertussis are nonmotile human pathogens, while Bordetella bronchiseptica expresses flagellin and causes disease in animals and immunocompromised human hosts.

What does Bordetella cause?

Pertussis, a respiratory illness commonly known as whooping cough, is a very contagious disease caused by a type of bacteria called Bordetella pertussis. These bacteria attach to the cilia (tiny, hair-like extensions) that line part of the upper respiratory system.

How do you identify Bordetella bronchiseptica?

Bordetella bronchiseptica They are oxidase positive and motile by peritrichous flagella. They are also nitrate and urease positive (usually within 4hr) which is a distinguishing factor from B. pertussis12.

How is Bordetella diagnosis?

Clinicians commonly use several types of laboratory tests to diagnose Bordetella pertussis. Scientists consider culture the gold standard because it is the only 100% specific method for identification. Other tests that can be performed include polymerase chain reaction (PCR) and serology.

What is pathogenesis of pneumonia?

PATHOGENESIS. Pneumonia indicates an inflammatory process of the lung parenchyma caused by a microbial agent. The most common pathway for the microbial agent to reach the alveoli is by microaspiration of oropharyngeal secretions.

What is Bordetella bronchiseptica?

Bordetella bronchiseptica (Fig. 16.22) is a cause of respiratory infections in a wide range of mammals. Bordetella bronchiseptica has been isolated from a variety of animal species, including pigs, rats, dogs, cats, guinea pigs and rabbits.

What animals are affected by Bordetella bronchiseptica?

Bordetella bronchiseptica has been isolated from a variety of animal species, including pigs, rats, dogs, cats, guinea pigs and rabbits.

What is the mode of transmission of bronchiseptica pneumoniae?

The main route of transmission for B. bronchiseptica is oral-nasal via direct aerosol droplets (mainly coughing). Infection is initiated by the attachment of B. bronchiseptica to the ciliated cells of the lungs (figure 2A).  Inside the lungs, it is able to evade the immune system and create ciliary dysfunction.

How does B bronchiseptica infect the body?

By paralyzing the cilia, B. bronchiseptica increases its chance for colonization and allows for other bacteria to colonize as well. Oftentimes, animals infected with B. bronchiseptica are infected with another bacteria or virus at the same time. B. bronchiseptica infects a broad range of mammals and gives rise to a wide spectrum of diseases.