Can I take cimetidine with clopidogrel?
Nurses should closely monitor patients who decide to continue proton pump inhibitor use for diminished efficacy of clopidogrel. Nurses should also advise patients not to take OTC omeprazole or OTC cimetidine with clopidogrel.
Can you take cimetidine with blood thinners?
Tagamet may interact with blood thinners, clopidogrel, phenytoin, nifedipine, metronidazole, propranolol, chlordiazepoxide, lidocaine, diazepam, theophylline, depression or anxiety medications. Tell your doctor all medications you use.
Does Tagamet interfere with Plavix?
Nov. 17, 2009 – The FDA today warned patients not to combine Plavix with Nexium, Prilosec, and nine other drugs — including Prozac and Tagamet. The drugs may make the anti-clotting drug Plavix dangerously less effective, the FDA says. They block an enzyme in the body that turns the drug into its active form.
Can you take omeprazole with Plavix?
FDA is recommending that the co-administration of clopidogrel (Plavix), a drug used to prevent blood clot formation, and omeprazole (Prilosec/Prilosec OTC), a proton pump inhibitor (PPI) used to reduce stomach acid, be avoided because omeprazole reduces the effectiveness of clopidogrel.
Can I take esomeprazole with clopidogrel?
Concomitant use of clopidogrel and omeprazole or esomeprazole is to be discouraged unless considered essential. Doctors should check whether patients who are taking clopidogrel are also buying over-the-counter omeprazole and consider whether other gastrointestinal therapies would be more suitable.
What drugs do cimetidine interact with?
Interactions
- Drug interactions may change how your medications work or increase your risk for serious side effects.
- Some products that may interact with this drug include: dofetilide, epirubicin, ticlopidine, artemether, clopidogrel, lumefantrine, metformin, moclobemide, moricizine, quinidine, silver sulfadiazine.
What drugs should not be taken with Plavix?
The Food and Drug Administration warned today that people who take the blood thinner clopidogrel (Plavix) should not take the heartburn drugs omeprazole (Prilosec, Prilosec OTC, and generics) and esomeprazole (Nexium) because two new studies confirm that the combination could have dangerous consequences.
What medications should not be taken with clopidogrel?
Clopidogrel may interact with other medications
- Diabetes drug. In most cases, repaglinide should not be taken with clopidogrel.
- Stomach acid drugs (proton pump inhibitors)
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
- Blood thinners.
- Drugs used to treat depression.
- Salicylates (aspirin)
- Opioids.
What antacid is safe with Plavix?
The FDA advises that if you are experiencing heartburn or acid reflux while taking Plavix, you should try using antacids ( Maalox, Mylanta, Rolaids, Tums and generics) and most H2 blockers such as famotidine (Pepcid), nizatidine (Axid) and ranitidine (Zantac), but not cimetidine (Tagamet, Tagamet HB, and generics).
What is the best painkiller to take with Plavix?
Usually, your doctor or pharmacist will recommend that you take acetaminophen (Tylenol) if you’re using Plavix. This is because acetaminophen is an over-the-counter (OTC) pain medication that’s least likely to cause bleeding.
What are the side effects of cimetidine oral with clopidogrel?
cimetidine oral decreases effects of clopidogrel oral by altering drug metabolism. Clopidogrel taken in this combination may inhibit platelet aggregation (increase your risk of bleeding). Serious – Use Alternative Avoid or Use Alternate Drug. cimetidine oral decreases effects of clopidogrel oral by affecting hepatic enzyme CYP2C19 metabolism.
Can I take cimetidine and proton pump inhibitors with clopidogrel?
Some proton pump inhibitors and cimetidine may slow down how quickly your liver processes clopidogrel to its active form. Your clopidogrel may not work as well or at all. Make sure your healthcare professionals (e.g. doctor or pharmacist) know that you are taking these medicines together.
Why is Plavix banned by FDA?
FDA Warns Plavix Patients of Drug Interactions. The drugs may make the anti-clotting drug Plavix dangerously less effective, the FDA says. They block an enzyme in the body that turns the drug into its active form. Plavix is the second most-prescribed drug in the world.
Why is Plavix less effective?
The drugs may make the anti-clotting drug Plavix dangerously less effective, the FDA says. They block an enzyme in the body that turns the drug into its active form. Plavix is the second most-prescribed drug in the world.