What CD45 1?
Description. CD45. 1 is an alloantigen of CD45, expressed by Ly5. 1 bearing mouse strains (e.g., RIII, SJL/J, STS/A, DA). CD45, a member of the protein tyrosine phosphatase (PTP) family, is a 180-240 kD glycoprotein expressed on all hematopoietic cells except mature erythrocytes and platelets.
What is CD45 antibody?
CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase (PTP) ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes. CD45 is absent on non-hematopoietic cell lines, normal and malignant, non-hematopoietic tissues.
Are B6 mice CD45 1 or CD45 2?
1 mice strains, under the assumption that the only difference between these mice and CD45. 2 B6 strain is the CD45 isoform.
What is a CD45 2 mice?
1 and CD45. 2, have been established as a marker system to track haematopoietic cells following congenic mouse bone marrow transplants. Despite the frequent use of this model for studying the impact of genetic modifications on relative differentiation potential, it is now evident that a bias exists in CD45.
What cells are positive for CD45?
CD45 antigen (leukocyte common antigen), a unique and ubiquitous membrane glycoprotein with a molecular mass of about 200 kDa, is expressed on almost all hematopoietic cells except for mature erythrocytes. However, the biological function of this glycoprotein still remains to be resolved.
Are all T cells CD3 positive?
CD3 (cluster of differentiation 3) is a protein complex and T cell co-receptor that is involved in activating both the cytotoxic T cell (CD8+ naive T cells) and T helper cells (CD4+ naive T cells). It is composed of four distinct chains….CD3 (immunology)
| CD3d molecule, delta | |
|---|---|
| Identifiers | |
| Alt. symbols | T3D |
| NCBI gene | 915 |
| HGNC | 1673 |
What is cdcd45 antibody?
CD45 Antibodies. CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase (PTP) ubiquitously expressed in all nucleated hematopoietic cells, comprising
What antibody detects mouse CD45?
CD45 Antibody (YKIX716.13) detects mouse CD45. Recognizes all CD45 isoforms as well as the known mouse CD45 alloantigens (CD45-1/Ly 5a and CD45-2/Ly 5b) Test in a species/application not listed above to receive a full credit towards a future purchase.
How does clone 30f11 recognize CD45 antigen?
Clone 30F11 recognizes the mouse CD45 antigen, also known as leukocyte common antigen (Ly-5), which is expressed at high levels on all cells of hematopoietic origin except for erythrocytes. Clone 30F11 reacts with all CD45 isoforms. CD45 can be used to discriminate leukocytes from non-hematopoietic cells.
What type of protein is CD45?
Description CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets.